[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"article-reid-hoffman-leaves-microsoft-board-manus-ai-en":3,"article-related-reid-hoffman-leaves-microsoft-board-manus-ai-en":30,"series-ai-agent-487edd3a-bc1d-4a3b-af82-b304fcb024f6":83},{"id":4,"slug":5,"title":6,"content":7,"summary":8,"source":9,"source_url":10,"author":11,"image_url":12,"cover_image":12,"category":13,"language":14,"translated_content":11,"related_article_id":15,"keywords":16,"key_takeaways":22,"views":26,"created_at":27,"published_at":28,"topic_cluster_id":29},"487edd3a-bc1d-4a3b-af82-b304fcb024f6","reid-hoffman-leaves-microsoft-board-manus-ai-en","Reid Hoffman leaves Microsoft board for Manus AI","\u003Cp data-speakable=\"summary\">Reid Hoffman is leaving \u003Ca href=\"\u002Ftag\u002Fmicrosoft\">Microsoft\u003C\u002Fa>’s board to focus on his AI drug discovery startup Manus.\u003C\u002Fp>\u003Cp>Reid Hoffman is stepping down from \u003Ca href=\"https:\u002F\u002Fwww.microsoft.com\" target=\"_blank\" rel=\"noopener\">Microsoft\u003C\u002Fa>’s board after nearly a decade, according to a regulatory filing disclosed Thursday. The LinkedIn co-founder said he wants to go “founder mode” with \u003Ca href=\"https:\u002F\u002Fmanus.com\" target=\"_blank\" rel=\"noopener\">Manus\u003C\u002Fa>, the AI drug discovery startup he co-founded, which has raised more than $50 million.\u003C\u002Fp>\u003Ctable>\u003Cthead>\u003Ctr>\u003Cth>項目\u003C\u002Fth>\u003Cth>數值\u003C\u002Fth>\u003C\u002Ftr>\u003C\u002Fthead>\u003Ctbody>\u003Ctr>\u003Ctd>Board tenure\u003C\u002Ftd>\u003Ctd>Nearly 10 years\u003C\u002Ftd>\u003C\u002Ftr>\u003Ctr>\u003Ctd>Microsoft bought LinkedIn\u003C\u002Ftd>\u003Ctd>$26.2 billion\u003C\u002Ftd>\u003C\u002Ftr>\u003Ctr>\u003Ctd>Microsoft first OpenAI investment\u003C\u002Ftd>\u003Ctd>$1 billion\u003C\u002Ftd>\u003C\u002Ftr>\u003Ctr>\u003Ctd>Inflection AI acqui-hire\u003C\u002Ftd>\u003Ctd>$650 million\u003C\u002Ftd>\u003C\u002Ftr>\u003Ctr>\u003Ctd>Manus funding\u003C\u002Ftd>\u003Ctd>Over $50 million\u003C\u002Ftd>\u003C\u002Ftr>\u003C\u002Ftbody>\u003C\u002Ftable>\u003Ch2>What changed\u003C\u002Fh2>\u003Cp>Hoffman joined Microsoft’s board in 2016, the same year Microsoft acquired LinkedIn for $26.2 billion. His exit closes a stretch that overlapped with Microsoft’s biggest AI bets, including its first $1 billion investment in \u003Ca href=\"\u002Ftag\u002Fopenai\">OpenAI\u003C\u002Fa> in 2019.\u003C\u002Fp>\n\u003Cfigure class=\"my-6\">\u003Cimg src=\"https:\u002F\u002Fxxdpdyhzhpamafnrdkyq.supabase.co\u002Fstorage\u002Fv1\u002Fobject\u002Fpublic\u002Fcovers\u002Finline-1780827472278-elag.png\" alt=\"Reid Hoffman leaves Microsoft board for Manus AI\" class=\"rounded-xl w-full\" loading=\"lazy\" \u002F>\u003C\u002Ffigure>\n\u003Cp>He was also an early OpenAI investor and stayed on that board until 2023, when he stepped down over conflict concerns. Those concerns widened after Microsoft struck a $650 million acqui-hire deal with Inflection AI, the startup Hoffman co-founded.\u003C\u002Fp>\u003Cul>\u003Cli>Hoffman says Manus is now far enough along to justify more direct involvement.\u003C\u002Fli>\u003Cli>Manus is led by CEO Dr. Siddhartha Mukherjee, the physician and Pulitzer Prize-winning author.\u003C\u002Fli>\u003Cli>Hoffman remains co-founder and chairman, but not CEO.\u003C\u002Fli>\u003Cli>The company has raised more than $50 million across two seed rounds, backed by General Catalyst.\u003C\u002Fli>\u003C\u002Ful>\u003Ch2>Why it matters\u003C\u002Fh2>\u003Cp>The move reduces one more overlap between Hoffman’s venture portfolio and Microsoft’s AI strategy. For boards and investors, it is another reminder that the same founders, backers, and acquirers are often spread across competing AI bets.\u003C\u002Fp>\n\u003Cfigure class=\"my-6\">\u003Cimg src=\"https:\u002F\u002Fxxdpdyhzhpamafnrdkyq.supabase.co\u002Fstorage\u002Fv1\u002Fobject\u002Fpublic\u002Fcovers\u002Finline-1780827470266-0kk0.png\" alt=\"Reid Hoffman leaves Microsoft board for Manus AI\" class=\"rounded-xl w-full\" loading=\"lazy\" \u002F>\u003C\u002Ffigure>\n\u003Cp>For developers and drug-discovery teams, Manus is part of a fast-growing push to use AI for chemistry, not just chatbots. Hoffman says the goal is “Move 37” AI for science: systems that can surface novel compounds, including potential cancer treatments.\u003C\u002Fp>\u003Cp>The timing also matters because AI drug discovery is moving from demos to trials. ByteDance’s Anew Labs has shown its first AI-designed therapy, and \u003Ca href=\"\u002Ftag\u002Fgoogle-deepmind\">Google DeepMind\u003C\u002Fa>’s Isomorphic Labs now has AI-designed candidates entering clinical testing.\u003C\u002Fp>\u003Cp>The key question is whether Manus can turn Hoffman’s hands-on shift into real output before larger players set the pace.\u003C\u002Fp>","Reid Hoffman is leaving Microsoft’s board after nearly a decade to focus on Manus, his AI drug discovery startup with $50M+ raised.","thenextweb.com","https:\u002F\u002Fthenextweb.com\u002Fnews\u002Freid-hoffman-leaves-microsoft-board-manus",null,"https:\u002F\u002Fxxdpdyhzhpamafnrdkyq.supabase.co\u002Fstorage\u002Fv1\u002Fobject\u002Fpublic\u002Fcovers\u002Finline-1780827472278-elag.png","ai-agent","en","066e5903-7569-402f-a397-f01468ffecd4",[17,18,19,20,21],"Reid Hoffman","Microsoft","Manus","AI drug discovery","OpenAI",[23,24,25],"Hoffman leaves Microsoft’s board after nearly 10 years to focus on Manus.","Manus has raised over $50 million and is led by Dr. Siddhartha Mukherjee.","The exit trims conflict risk as Hoffman’s AI investments intersected with Microsoft and OpenAI.",0,"2026-06-07T10:17:21.75719+00:00","2026-06-07T10:17:21.744+00:00","da66ce76-5ea5-4718-9ace-7b8307dfaf18",{"tags":31,"relatedLang":42,"relatedPosts":46},[32,34,36,38,40],{"name":18,"slug":33},"microsoft",{"name":19,"slug":35},"manus",{"name":21,"slug":37},"openai",{"name":17,"slug":39},"reid-hoffman",{"name":20,"slug":41},"ai-drug-discovery",{"id":15,"slug":43,"title":44,"language":45},"reid-hoffman-leaves-microsoft-board-manus-ai-zh","霍夫曼離開微軟董事會，轉向 Manus","zh",[47,53,59,65,71,77],{"id":48,"slug":49,"title":50,"cover_image":51,"image_url":51,"created_at":52,"category":13},"9ed3ac8c-2c79-40ae-982e-bf0450bf40dd","how-to-understand-codex-chatgpt-merge-en","How to understand the Codex and ChatGPT 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OpenAI","https:\u002F\u002Fxxdpdyhzhpamafnrdkyq.supabase.co\u002Fstorage\u002Fv1\u002Fobject\u002Fpublic\u002Fcovers\u002Finline-1780398173367-8lyd.png","2026-06-02T11:02:26.247565+00:00",{"id":78,"slug":79,"title":80,"cover_image":81,"image_url":81,"created_at":82,"category":13},"1b25f514-9ed1-4c6f-b9d7-f56eb34033f5","build-production-rag-with-langchain-in-8-steps-en","Build Production RAG with LangChain in 8 Steps","https:\u002F\u002Fxxdpdyhzhpamafnrdkyq.supabase.co\u002Fstorage\u002Fv1\u002Fobject\u002Fpublic\u002Fcovers\u002Finline-1780178601812-0o68.png","2026-05-30T22:02:48.810322+00:00",[84,89,94,99,104,109,114,119,124,129],{"id":85,"slug":86,"title":87,"created_at":88},"03db8de8-8dc2-4ac1-9cf7-898782efbb1f","anthropic-claude-ai-agent-task-automation-en","Anthropic's Claude AI Agent: A New Era of Task 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